Case Study: Droplet generation with the mp6 micropump and microfluidic chips
Droplet-based microfluidic systems have found their way into laboratories as it is possible to generate (monodisperse) droplets in the femto- to nanoliter scale. So, they opened up unlimited experimental possibilities like digital PCR and single cell experiments where the compartmentalization and surface-to-volume ratio are important.
Droplet generation in microfluidics is based on the use of two immiscible phases that are referred to as the continuous phase (oil, medium in which droplets flow) and dispersed phase (water, the droplet). For generating droplets, microfluidic systems generally include a microfluidic chip, a fluid handling system and tubing. This system is usually connected to a computer and a microscope to visualize droplet formation.